Tissue Receptor

Tissue receptors, also known as cellular or cell surface receptors, are protein molecules, often found in the plasma membrane, that bind to specific extracellular ligands. This binding initiates signal transduction pathways, altering cell function. They are diverse and include ion channels, GPCRs, RTKs, and intracellular/nuclear receptors. They play crucial roles in cell communication, metabolism, immunity, and development, and are implicated in diseases like cancer, autoimmune disorders, and neurological conditions.

Other names

Cell Surface ReceptorCellular Receptor

Ligand binding triggers conformational changes, leading to ion channel opening/closing, G protein activation, phosphorylation cascades, or direct gene transcription modulation.