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Tissue regeneration and repair refers to the complex, multi-phase process by which living organisms restore structure and function to tissues following injury or damage. This biological process involves inflammation, proliferation, differentiation, and remodeling, and is orchestrated by numerous growth factors (such as PDGF, EGF, and TGF-beta), cytokines, and specialized cells (e.g., fibroblasts, stem cells, immune cells)[1][6]. While some tissues (like skin and liver) possess high regenerative capability, others (like heart and central nervous system) display limited potential. Failure in tissue regeneration or repair mechanisms can lead to excessive scar formation (fibrosis), chronic wounds, or inadequate tissue function[1][2][5].
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