Target intelligence / Profile preview

Titanium dioxide (TiO₂)

Target
TiO₂
Molecular classification
Other
01

Overview

Titanium dioxide is an inorganic, white powdered metal oxide with the chemical formula TiO₂, commonly found in three main crystalline forms—rutile, anatase, and brookite—where octahedral coordination of Ti(IV) by oxygen occurs[1][2][3][7]. It is extensively used as a pigment in paints, coatings, plastics, food products, and sunscreens due to its high refractive index, strong UV light absorption, photo(electro)chemical stability, nontoxicity, and whiteness[2][3][7]. Titania is not a protein, receptor, enzyme, or other biomolecular therapeutic target but is prized in materials and industrial chemistry. Safety concerns focus primarily on inhalation of dust, particularly ultrafine or nanoparticle forms, which have been linked to respiratory health risks and possible carcinogenicity in occupational settings[3][7]. Titanium dioxide is **not a therapeutic target** such as a receptor, enzyme, or transporter; rather, it is a widely used industrial and cosmetic material. Its inclusion as a "target" is incorrect, as it does not play a direct role as a molecular target in pharmacology or drug discovery contexts[3][7].

Other names
titanium(IV) oxidetitaniatitanium whitePigment White 6PW6CI 77891E171TIO2Rutile titanium dioxideTitaniAnano titanium dioxideAnataseTi02hombitan
02

Safety considerations

Carcinogenicity (classified as possibly carcinogenic to humans by IARC: Group 2B, especially inhaled particles)Respiratory hazard when inhaled as dustNot significantly toxic in oral exposures at usual levelsRegulatory concerns regarding food and cosmetic uses in some jurisdictions[3][7]

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