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TMEM132D antisense RNA 2 (TMEM132D-AS2) is a long non-coding RNA (lncRNA) gene located on chromosome 12 (hg38: chr12:129208601-129212662)[3][5]. It is classified as an antisense RNA, meaning it is transcribed from the DNA strand opposite to the TMEM132D protein-coding gene. While very little is known about its function, lncRNAs of this type are often involved in the regulation of gene expression at the transcriptional or post-transcriptional level. There is currently no direct experimental evidence linking TMEM132D-AS2 to specific biological pathways, diseases, or drug interactions. Its closest coding neighbor, TMEM132D, is implicated in anxiety and neuropsychiatric phenotypes, but such roles have not yet been attributed to TMEM132D-AS2. Key points: - TMEM132D-AS2 is not a receptor, drug target, or protein. - It is a non-coding RNA (lncRNA), likely acting (if functional) as a regulatory RNA. - No documented drug interactions, biomarker roles, or therapeutic targeting. - Not associated with any well-established safety or therapeutic concerns.[3][4][5]
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