TMEM230 pseudogene 1 (TMEM230P1)

TMEM230 pseudogene 1 (TMEM230P1) is a pseudogene, meaning it is a non-functional genomic sequence similar to the TMEM230 gene but does not encode a functional transmembrane protein. Pseudogenes lack the molecular properties and disease associations of their parent genes. The functional TMEM230 protein is a multi-pass transmembrane protein, highly expressed in the neuronal vesicles and vascular compartments, and implicated in the trafficking and recycling of synaptic vesicles, neurodegeneration (e.g., Parkinson's disease, dementia), and tumor angiogenesis[1][2][3][4]. There is no evidence in the literature linking TMEM230P1 itself to disease, drug interactions, biomarkers, or any therapeutic applications. If your interest is in the druggable target, disease roles, or biology of TMEM230, consult entries for TMEM230 (Transmembrane Protein 230), not TMEM230P1 or any other pseudogene variants[4]. The parent gene and protein are relevant for synaptic vesicle trafficking, neurodegeneration, angiogenesis, and may constitute a therapeutic target[1][2][3][4]. Pseudogenes, such as TMEM230P1, do not typically produce a functional product and do not qualify as receptors or therapeutic targets.