TMEM30B pseudogene 1 (TMEM30BP1)

TMEM30BP1 (TMEM30B pseudogene 1) is a pseudogene related to the TMEM30B gene, which encodes the accessory beta subunit (CDC50B) of the phospholipid flippase complex (P4-ATPase family). Pseudogenes are genomic segments resembling known genes but typically lack coding potential and are not translated into functional proteins; they may arise from gene duplication or retrotransposition events[4][5]. Unlike TMEM30B, which participates in membrane lipid transport and cellular signaling, TMEM30BP1 is not known to encode a functional product or have confirmed biological activity. Pseudogenes can sometimes regulate their parent gene via RNA interactions, but there is no data supporting such a role for TMEM30BP1 at this time. TMEM30B itself is expressed in various human tissues and has roles in membrane lipid asymmetry, vesicle formation, and possibly disease, but TMEM30BP1 is not cataloged as a therapeutic target nor implicated in disease or drug interactions[1][2][3]. The existence of “TMEM30B pseudogene 1” is documented in genome annotation, but it is not considered a canonical target in pharmacology or biomedical research[4]. Confusion may arise if TMEM30BP1 is mistaken for the functional TMEM30B gene product (CDC50B), which is a membrane protein and not a pseudogene[1][2][3].

Other names

TMEM30BP1TMEM30B pseudogene 1