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TMEM51 antisense RNA 2 (TMEM51-AS2)

Target
TMEM51-AS2
Molecular classification
Long non-coding RNA, lncRNA
01

Overview

TMEM51 antisense RNA 2 (TMEM51-AS2) is classified as a long non-coding RNA (lncRNA) gene, officially designated as TMEM51-AS2, with HGNC symbol 32332. It is annotated as an RNA gene with no established coding potential and belongs to the lncRNA class. There is extremely limited information available in the scientific literature or major gene/protein databases regarding its function, biological roles, or disease relevance. Most current knowledge is restricted to its genomic identity and classification as a non-coding RNA. No evidence has been identified to support a direct therapeutic targeting role, biological function, drug interaction, or established disease association for TMEM51-AS2. Important clarification: Much of the available data and functional characterization, especially regarding cancer biology, RNA methylation, and immune regulation, refers to a related lncRNA, TMEM51-AS1, not to TMEM51-AS2. There is a risk of confusion in the literature and databases owing to the similar names, but the available information for TMEM51-AS2 specifically is extremely sparse. If referring to functional or disease relevance, it is likely you meant TMEM51-AS1, which has documented effects as a tumor suppressor in colorectal cancer and roles in RNA methylation, immune modulation, DNA repair, and response to anticancer drugs. TMEM51-AS2 remains an obscure lncRNA without evidence for therapeutic target classification or detailed annotation in current scientific sources. If functionally characterized antisense lncRNAs for TMEM51 are required, TMEM51-AS1 is the molecule of interest with relevant disease and functional annotations.

Other names
C1orf195
02

Biological functions

Gene expression regulation (by antisense RNA mechanisms)Potential involvement in RNA methylation and signal transduction (by analogy with TMEM51-AS1)
03

Disease associations

No direct evidence for TMEM51-AS2Possible involvement in cancer (by analogy to TMEM51-AS1)

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