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TMSB15B antisense RNA 1 (TMSB15B-AS1)
- Target
- TMSB15B-AS1
- Molecular classification
- Other (long noncoding RNA, antisense RNA)
01
Overview
TMSB15B antisense RNA 1 (TMSB15B-AS1) is a long noncoding antisense RNA (asRNA) gene annotated in the human genome. It is transcribed from the region opposite to the protein-coding gene TMSB15B, which codes for Thymosin Beta 15B, an actin-binding protein involved in cell migration and cytoskeletal dynamics. As a noncoding antisense transcript, TMSB15B-AS1 may modulate the expression of the TMSB15B gene or influence chromatin state locally, although its specific biological roles and functions are not well characterized in current literature. The general class of antisense RNAs is implicated in gene regulation via base pairing with sense mRNA, affecting RNA stability, transcription, or translation, and may function in cis or trans depending on context, but no disease association or pharmacological targeting for this specific antisense RNA is established.
- Other names
- TMSB15B antisense RNA 1NR_146556.1
02
Mechanism of action
No drugs targeting this molecule have characterized mechanisms of action.
03
Biological functions
Interacts with genomic DNA or TMSB15B sense transcriptPutative regulation of gene expression in cis or trans as an antisense RNAInferred modulator of local chromatin, transcription, or RNA stability
04
Disease associations
Other. There are no well-established associations with specific diseases, according to current gene databases (GeneCards, BioGPS)
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