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TMSB4X pseudogene 1 (TMSB4XP1) is a non-functional, transcribed but not translated pseudogene related to the TMSB4X gene, which encodes thymosin beta 4. Pseudogenes like TMSB4XP1 generally arise from duplication or retrotransposition events resulting in gene copies that have lost functional protein-coding ability due to mutations or lack of regulatory elements. No functional protein is produced from TMSB4XP1, and it is not implicated in known biological processes or disease mechanisms[5]. Key point: TMSB4XP1 is a pseudogene and not a valid therapeutic target. For biological or disease relevance, refer to the functional gene TMSB4X, not TMSB4XP1. Any research or therapeutic interest should focus on TMSB4X, not its pseudogene.
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