TOMM20 pseudogene 4 (TOMM20P4)

TOMM20 pseudogene 4 (TOMM20P4) is a human pseudogene, meaning it is a segment of DNA that resembles a functional gene (in this case, the gene encoding translocase of outer mitochondrial membrane 20, or TOMM20) but has lost its ability to code for a functional protein due to accumulating disabling mutations. There is no evidence it is translated into protein or possesses biological function in health or disease, nor is there any therapeutic implication reported for this pseudogene[5][6]. TOMM20P4 is not a receptor, enzyme, transporter, or functional therapeutic target. The canonical functional gene is TOMM20, and any disease relevance or druggability discussed in the literature relates to TOMM20, not its pseudogenes[1][2][3][5]. TOMM20P4 is only cataloged as a genomic sequence of similarity to TOMM20, but it is classified as a pseudogene and not a functional coding gene[5]. There are no known aliases besides TOMM20P4, and no biological pathways, cellular functions, disease associations, therapeutic or biomarker implications, or safety considerations have been established for this locus[5]. Any structured target profiling should clearly distinguish the functional gene (TOMM20) from this inactive pseudogene (TOMM20P4).

Other names

TOMM20P4