TOMM5 pseudogene 1 (TOMM5P1)

TOMM5 pseudogene 1 (TOMM5P1) is a non-functional copy related to the TOMM5 gene, which encodes a component of the mitochondrial outer membrane translocase complex responsible for protein insertion into the mitochondrial outer membrane[1][5]. As a pseudogene, TOMM5P1 does not encode a functional protein and is not considered a therapeutic target. Pseudogenes such as TOMM5P1 arise from duplication or retrotransposition events and accumulate mutations that render them inactive[3]. TOMM5 is the functional gene, involved in mitochondrial protein import and associated with rare mitochondrial disorders[1][5]. TOMM5P1, by definition as a pseudogene, is not a protein-coding gene, has no known functional role, and is not a therapeutic target. The presence of "pseudogene 1" in the name signifies it is an inactive genomic element, not a functional molecular target. If you are seeking information about the functional target, refer instead to Translocase of outer mitochondrial membrane 5 (TOMM5).

Other names

Translocase of outer mitochondrial membrane 5 pseudogene 1

None (pseudogenes do not produce active proteins)