Target intelligence / Profile preview

Tooth Enamel Mineral (Hydroxyapatite) (N/A)

Target
N/A
Molecular classification
Mineral, Calcium Phosphate, Biomaterial
01

Overview

Tooth enamel is the highly mineralized outer layer of teeth, composed primarily of hydroxyapatite. It provides a protective barrier against physical and chemical damage. While enamel cannot regenerate, it can undergo limited remineralization. Its primary function is to protect the underlying dentin and pulp from mechanical forces, temperature extremes, and acids. The mineral composition includes calcium, phosphate, magnesium, and fluoride. Its structural organization into rods contributes to its hardness and brittleness.

Other names
EnamelHydroxyapatiteCalcium PhosphateTooth Mineral
02

Mechanism of action

Fluoride enhances remineralization of enamel and inhibits bacterial acid production. Chlorhexidine is an antibacterial agent that reduces plaque formation. Xylitol inhibits bacterial metabolism.

03

Biological functions

Tooth protectionMechanical supportAcid resistanceRemineralization (limited)
04

Disease associations

Dental cariesEnamel hypoplasiaTooth erosionFluorosisAmelogenesis imperfecta
05

Safety considerations

Fluorosis (excessive fluoride intake)Tooth sensitivity (after erosion or damage)Brittle enamel (due to mineral imbalance)
06

Interacting drugs

Fluoride

2 more in the full profile.

07

Biomarkers

Salivary calcium levelsSalivary phosphate levelsSalivary fluoride levelsPlaque pH

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