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Tousled like kinase 1 pseudogene 1 (TLK1P1), also known as TLK1ps, is classified as a pseudogene of the Tousled like kinase 1 (TLK1) gene[1]. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they do not encode a functional protein and typically do not produce a biologically active molecule. TLK1P1 does not have documented biological functions, roles in disease, or therapeutic targeting relevance. The functional, protein-coding gene in this family is TLK1, which acts as a serine/threonine kinase involved in chromatin assembly, DNA replication, and the DNA damage response. However, TLK1P1 itself is not an active kinase, enzyme, or receptor, and is not considered a therapeutic target or biomarker[1].
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