Target intelligence / Profile preview

Transcription elongation factor A N-terminal and central domain containing 2 (TCEANC2)

Target
TCEANC2
Molecular classification
Other
01

Overview

Transcription elongation factor A N-terminal and central domain containing 2 (TCEANC2) is a protein-coding gene located on chromosome 1 (human), encoding a protein that is predicted to regulate transcription by RNA polymerase II and to function within the cell nucleus. The principal role appears to be modulation of gene transcription, with broad tissue expression and nuclear localization. While genetic association studies suggest some relevance to diseases, such as breast adenoid cystic carcinoma, TCEANC2 is not currently established as a direct therapeutic target, diagnostic biomarker, or drug-interaction partner. It shares sequence domains similar to factors involved in transcription elongation, but its precise physiological role is not fully characterized; no experimental evidence currently supports direct molecular function or disease-driving effects.

Other names
C1orf83Chromosome 1 open reading frame 83FLJ32112Transcription elongation factor A (SII) N-terminal and central domain-containing 2Transcription elongation factor A N-terminal and central domain-containing protein 2
02

Mechanism of action

None known

03

Biological functions

Regulation of transcription by RNA polymerase IIProtein bindingNuclear localization
04

Disease associations

Associated with breast adenoid cystic carcinoma

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