Target intelligence / Profile preview

Transcription Factor (TF)

Target: TF
Molecular classification: Transcription factor

Overview

A transcription factor (TF) is a protein that regulates the transcription of genetic information from DNA to messenger RNA by binding to specific DNA sequences. These proteins play a central role in controlling when, where, and how genes are turned on or off within cells. By influencing gene expression, TFs ensure that genes are expressed at the right time, in the right cell type, and at appropriate levels throughout an organism's life.

Mechanism of action

Drugs disrupt interaction with cofactors or degrade the TF directly.

Biological functions

Regulation of gene expressionCell divisionGrowthDifferentiationCell migrationApoptosisResponse to external signals

Disease associations

Cancer

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