Transcription factor AP-2 delta (TFAP2D)

Transcription factor AP-2 delta (TFAP2D) is a protein-coding gene that encodes a sequence-specific DNA-binding transcription factor[1][2][3][7]. It regulates gene transcription by interacting with viral and cellular enhancer elements, binding to the consensus sequence 5'-GCCNNNGGC-3', and activating or repressing gene expression involved in critical biological processes such as cell proliferation and developmental pathways[1][3][7]. TFAP2D is implicated in transcriptional regulation, cell population proliferation, and neuronal development, and has been associated with diseases including cancer, Char syndrome, and branchiooculofacial syndrome[1][5].

Other names

Transcription factor AP-2 deltaTFAP2DAP-2 deltaTFAP2BL1AP2-deltaAP-2deltaActivating enhancer-binding protein 2-deltaTranscription factor AP-2-beta-like 1AP-2 likeactivating enhancer binding protein 2 beta-like 1activating enhancer-binding protein 2-deltatranscription factor AP-2 beta (activating enhancer-binding protein 2 beta)-like 1