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transcription factor IIA small 12 kDa subunit pseudogene

Molecular classification
Pseudogene
01

Overview

This entry refers to a pseudogene related to the small (gamma, 12 kDa) subunit of transcription factor IIA (TFIIA). TFIIA is a general (basal) transcription factor required for RNA polymerase II-dependent transcription, playing key roles in promoter recognition and formation of the transcription preinitiation complex[1][4][6]. The functional subunit is encoded by GTF2A2, while ENSG00000233575 represents a non-coding, likely non-functional pseudogene. As such, it is not a functional target, does not serve as a therapeutic target, and has no known roles in disease, drug interaction, or biomarker utility. Key details: - The true protein-coding gene for this function is GTF2A2, which encodes the gamma (12 kDa) subunit of transcription factor IIA[4][6]. - Pseudogenes are non-functional copies of genes and do not produce active proteins or serve as direct drug targets. - No information is available about drugs, mechanism of action, biomarkers, or safety concerns, confirming that this entry is not a therapeutic target and is best described as an error or non-applicable for drug development purposes. If you require information about the functional gene, you should refer to "Transcription factor IIA small 12 kDa subunit" (GTF2A2, not the pseudogene), which is a component of the general transcription machinery in eukaryotes[4][6].

Other names
Transcription factor IIA gamma subunit pseudogeneTFIIA gamma pseudogeneGTF2A2 pseudogene

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