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The **anticodon** is a trinucleotide sequence found in the anticodon loop of every transfer RNA (tRNA) molecule. Each anticodon is complementary to a corresponding codon in messenger RNA (mRNA), enabling the tRNA to deliver the correct amino acid during protein synthesis. The anticodon ensures the fidelity of translation by pairing with one or more specific codons, with some tRNAs using "wobble" base pairing to recognize multiple codons for the same amino acid[5][6][7]. Although the anticodon is essential for the function of tRNAs in gene expression and the accurate synthesis of proteins, it is a nucleotide motif within tRNA, not a molecule or receptor that can be targeted directly by drugs or therapeutic interventions[1][2][3][6]. **Note:** - The query "tRNA anticodons)" has issues: the entry is not a molecule, receptor, or canonical target; the parentheses suggest a typographic or input error. - tRNA anticodons are essential components of tRNAs but should not be listed as stand-alone therapeutic targets. - No direct drugs, mechanisms of action, or safety concerns are associated specifically with tRNA anticodons, only with enzymes or modifications acting on them[1].
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