Transgelin 2 pseudogene 2 (TAGLN2P2)

Transgelin 2 pseudogene 2 (TAGLN2P2, ENSG00000254316) is classified as a **pseudogene**, meaning it is a genomic DNA sequence similar to the transgelin 2 gene (TAGLN2), but is nonfunctional and does not encode a protein[2]. Pseudogenes are generally produced through gene duplication or retrotransposition followed by mutational loss of function. They are not considered therapeutic targets and have no known established role as a biomarker, drug target, or disease-associated gene. They may sometimes play regulatory roles or be implicated in gene expression control, but no such role is currently attributed to TAGLN2P2 in the literature[2].\n\n**Key points:** \n- This entry is distinct from the protein-coding **Transgelin 2** gene (TAGLN2), which is an actin-binding protein involved in cytoskeletal regulation, cell migration, immune function, and cancer progression[1][3][5], and which can be considered a therapeutic target. \n- TAGLN2P2 itself is just a pseudogene and does **not** code for a protein, does **not** serve as a drug target, and does **not** have known direct disease relevance[2].\n\n**If searching for information about therapeutic targets, regulatory genes, or disease-associated proteins, use the protein-coding gene \"TAGLN2\" (Transgelin 2) instead of the pseudogene \"TAGLN2P2\"[2].**

Other names

Transgelin 2 Pseudogene 2TAGLN2P2ENSG00000254316