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TRPC6 pseudogene 5 (TRPC6P5) is a human pseudogene related to the functional TRPC6 gene. Pseudogenes are genomic DNA sequences similar to known genes but generally non-functional due to mutations or lack of critical regulatory elements. TRPC6P5 does not encode an active calcium channel and is not considered a receptor, enzyme, or any typical drug target. In contrast, its related functional gene, TRPC6, encodes a calcium-permeable cation channel that plays important roles in kidney podocytes, immune cells, smooth muscle contraction, and disease states such as focal segmental glomerulosclerosis and pulmonary hypertension[2][8][10]. If your inquiry intended the functional channel TRPC6 (not TRPC6P5), please clarify; otherwise, the above reflects structured information for the identified pseudogene.
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