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Transient receptor potential cation channel subfamily V member 6 (TRPV6)

Target: TRPV6
Molecular classification: Ion channel, TRP channel, Calcium channel

Overview

TRPV6 is a highly calcium-selective ion channel belonging to the transient receptor potential (TRP) family, specifically the vanilloid subfamily. It plays a crucial role in calcium absorption and homeostasis in mammals. Overexpression has been linked to cancer cell proliferation and poor prognosis in certain tumors; thus it represents an emerging target for cancer therapy research.

Biological functions

Calcium absorptionCalcium homeostasisTranscellular calcium transport

Disease associations

Cancer

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