Translocase of outer mitochondrial membrane 20 homolog pseudogene

The translocase of outer mitochondrial membrane 20 homolog pseudogene (ENSG00000275400) is a pseudogene in humans related to the TOMM20 gene. It does not code for a functional protein, enzyme, transporter, or receptor. TOMM20 itself is a mitochondrial import receptor subunit involved in protein import into mitochondria, but the pseudogene does not participate in these biological processes. Pseudogenes such as ENSG00000275400 are generally non-functional remnants of genes that have lost their protein-coding ability through evolution. Key distinctions and context: - The functional gene, TOMM20 (mitochondrial import receptor subunit TOM20 homolog), is a component of the protein import machinery in mitochondria and may be found in related databases with synonyms like TOMM20, MAS20, MOM19, and TOM20. - ENSG00000275400 is specifically a pseudogene and should not be confused with the functional TOMM20 protein, which acts as a receptor for mitochondrial protein translocation. If a therapeutic or mechanistic interest is in TOMM20 as a protein, that would be a different, functional gene (e.g., ENSG00000100239), not the pseudogene ENSG00000275400.

Other names

TOMM20 pseudogeneTOMM20Ptranslocase of outer mitochondrial membrane 20 homolog pseudogene (yeast)