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Translocase of outer mitochondrial membrane 22 homolog pseudogene

Molecular classification
Pseudogene
01

Overview

This gene, ENSG00000213287 (also known as LOC101929104 or "translocase of outer mitochondrial membrane 22 homolog pseudogene"), is a **pseudogene** related to the gene encoding the mitochondrial import receptor subunit TOM22 (TOMM22)[4][7]. Pseudogenes are defective copies of protein-coding genes, often the result of gene duplication or retrotransposition, which accumulate mutations and lose their protein-coding potential[2][6][8]. They are usually non-functional as proteins but can sometimes be transcribed into non-coding RNAs with regulatory roles affecting their parent genes or other genetic pathways[2][6]. There are no known functional, therapeutic, or biomarker roles for this specific pseudogene, and it does not encode a functional receptor, enzyme, or any canonical drug target[4][7][1]. It is not a suitable therapeutic target and is likely annotated for genomic completeness rather than any direct biological or pharmacological significance[2][4][6].

Other names
LOC101929104TOMM22 pseudogeneENSG00000213287
02

Biological functions

Regulation of gene expression via non-coding RNA (potential, general for pseudogenes)[2][6][8]Source of long non-coding RNAs (potential, general for pseudogenes)[2][6][8]
03

Disease associations

Other (Pseudogenes can be associated with human disease processes, especially cancer or as competing endogenous RNAs, but there is no evidence for this specific pseudogene)[2][6]

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