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Transmembrane and coiled-coil domain-containing protein 2 (**TMCO2**) is a protein encoded by the *TMCO2* gene in humans.[7][8] It is a predicted integral membrane protein containing coiled-coil domains, but its precise biological function is not yet characterized. The *TMCO2* gene is present in the membrane, but specific subcellular localization, molecular function, and physiological or pathological roles remain unknown. No drugs are known to interact with TMCO2, and it is not considered a classic therapeutic target at present.[5][8]
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