Transmembrane and tetratricopeptide repeat containing 1 pseudogene (TMTC1 pseudogene (ENSG00000276431))

This locus, ENSG00000276431, is annotated as a pseudogene related to the transmembrane and tetratricopeptide repeat containing 1 gene (TMTC1). Pseudogenes are segments of DNA similar to known protein-coding genes but are rendered nonfunctional due to disabling mutations such as frameshifts, premature stop codons, or loss of regulatory elements; they no longer produce functional protein products. Pseudogenes like TMTC1 pseudogene are generally not involved in typical molecular functions associated with therapeutic targets and do not participate in signaling, enzymatic activity, or transport. Although some pseudogenes have been reported to serve regulatory, evolutionary, or biomarker roles, there is no evidence that TMTC1 pseudogene is involved in disease, drug response, or clinical applications at present. Its identification may complicate genetic assays (PCR, sequencing) due to sequence similarity with its parent gene, but its functional relevance remains null for therapeutic development.

Other names

Transmembrane and tetratricopeptide repeat containing 1 pseudogeneTMTC1 pseudogeneENSG00000276431