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Transmembrane and tetratricopeptide repeat containing 4 pseudogene (LOC729707)
- Target
- LOC729707
- Molecular classification
- Other (Pseudogene)
01
Overview
“Transmembrane and tetratricopeptide repeat containing 4 pseudogene” (LOC729707, ENSG00000248560) is a genomic locus that corresponds to a nonfunctional copy of the TMTC4 gene. Pseudogenes are typically copies of protein-coding genes that have lost the ability to code for functional proteins due to mutations, truncations, or lack of proper regulatory elements[3][7]. LOC729707 is located on human chromosome 5[3], defined as a pseudogene of TMTC4. There is no evidence that LOC729707 encodes an active protein or fulfills a biological function, nor is it considered a therapeutic target.
- Other names
- LOC729707Transmembrane O-mannosyltransferase targeting cadherins 4 pseudogeneTMTC4 pseudogene
02
Mechanism of action
None
03
Biological functions
None explicitly known for the pseudogene; does not encode a functional protein
04
Disease associations
None definitely established for the pseudogene; functional TMTC4 is associated with deafness and possibly cancer
05
Biomarkers
None definite for the pseudogene; functional TMTC4 is a marker for prostate cancer
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