Transmembrane protein 121B (TMEM121B)

Transmembrane protein 121B (TMEM121B) is a protein-coding gene found in humans (located on chromosome 22) and other mammals. Also known as Cat eye syndrome critical region protein 6 (CECR6), this protein is predicted to be a component of cellular membranes but its biological function remains uncharacterized. TMEM121B is listed among the genes in the Cat Eye Syndrome critical region, a chromosomal segment whose duplication causes syndromic features, suggesting a potential role in genetic disorders arising from chromosomal abnormalities. There is no evidence indicating TMEM121B is a therapeutic target, a functionally characterized channel/receptor/enzyme, or a current focus of targeted drug development. As such, it is best classified as an **uncharacterized membrane protein** with ambiguous function and uncertain disease relevance beyond chromosomal disorders.

Other names

Cat eye syndrome critical region protein 6CECR6Cat eye syndrome chromosome region, candidate 6TMEM121B, cat eye syndrome critical region protein 6