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Transmembrane protein 167B (TMEM167B)
- Target
- TMEM167B
- Molecular classification
- Other (Transmembrane protein), Structural protein (Located in Golgi membrane; not a typical receptor, enzyme, or channel)
01
Overview
Transmembrane protein 167B is a membrane-associated structural protein located primarily in the Golgi apparatus and involved in the early stages of the constitutive secretory pathway, including vesicle trafficking and protein sorting. TMEM167B does not act as a classical receptor, transporter, or enzyme and currently lacks evidence of direct involvement in human diseases or interaction with drugs. Its key role is structural and organizational within the Golgi, ensuring proper cellular protein handling and secretion[1][3][12][13].
- Other names
- Protein kish-BC1orf119AD-020FLJ907102010200O16RikProtein X 013 homologRGD1564454
02
Biological functions
Constitutive secretory pathway (participates in vesicle traffic and protein sorting within the Golgi)Golgi apparatus-associated processes
03
Disease associations
Other (Not directly implicated in major diseases; no strong association with cancer, inflammation, neurodegeneration, or cardiovascular disease as of Sep 2025)
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