Transmembrane protein 179B (TMEM179B)

Transmembrane protein 179B is a poorly characterized, predicted 4-pass transmembrane protein that belongs to the TMEM179 family. It encodes a human protein of 219 amino acids, with no conserved Pfam domain or established molecular function. TMEM179B and its family member TMEM179 share approximately 38% sequence identity but neither is functionally annotated beyond their putative transmembrane domain structure[2][5]. No proven involvement in receptor, transporter, or enzyme activity exists. The broader family of four-transmembrane proteins (4TM) is structurally related to miscellaneous transmembrane proteins that may play roles in cell communication, adhesion, or scaffolding functions, but TMEM179B is not classified in any specific subclass, nor does it have documented disease linkage. Tissue expression or co-expression data are not sufficiently detailed to infer functionality. Currently, TMEM179B represents an uncharacterized membrane protein awaiting further biological and pharmacological study[2][5].

Other names

TMEM179BTransmembrane protein 179BHGNC:33744NCBI Gene:374395Ensembl: ENSG00000185475UniProtKB: Q7Z7N9Previous GeneCards identifiers (series GC11P...)

Not applicable. No mechanism of action reported, as no drugs target this protein.