Transmembrane protein 183A (TMEM183A)

Transmembrane protein 183A (TMEM183A) is a protein-coding gene found on human chromosome 1. It is predicted to encode an integral membrane protein and is thought to be part of the SCF ubiquitin ligase complex, suggesting a possible role in the regulation of protein stability and ubiquitination pathways. The precise biological function is not fully characterized, and there are currently no known drug interactions, mechanisms of action, or established roles as a therapeutic target. Variants of this gene are associated with some diseases such as autosomal recessive deafness (DFNB63) and inflammatory bowel disease 7, but beyond genetic association, detailed mechanistic roles remain to be elucidated[1][4][6][12][14].

Other names

C1orf37Chromosome 1 open reading frame 37