Transmembrane protein 200B (TMEM200B)

Transmembrane protein 200B (TMEM200B) is a protein-coding gene predicted to encode a membrane protein, with localization in cell membranes as part of the DUF2371 (domain of unknown function 2371) family. Its precise molecular and biological functions in humans are unknown, and there is no direct evidence of it acting as a receptor, transporter, or enzyme. Some expression is noted across tissues, and genetic association exists with anal canal squamous cell carcinoma, but its mechanistic involvement in disease remains unclear. There are no established biomarkers or drugs clinically targeting TMEM200B, and no direct safety or therapeutic data are described[1][3][5][8][9][10].

Other names

Transmembrane protein 200BTMEM200BTTMBTransmembrane protein TTMATwo transmembrane domain-containing family member Btransmembrane protein TTMA