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TMEM230P2 is a pseudogene related to the Transmembrane Protein 230 (TMEM230) gene. It is a genomic sequence similar to TMEM230 but does not encode a functional protein. Pseudogenes typically arise from gene duplication or retrotransposition events, and they usually lack biological activity. While TMEM230 is implicated in synaptic vesicle trafficking, angiogenesis, neurodegenerative diseases, and cancer, there is no evidence that TMEM230P2 encodes a protein or functions as a therapeutic target[5]. Notes: - TMEM230P2 should not be confused with the functional TMEM230 gene or its protein product; TMEM230P2 itself does not have a direct role in drug targeting or disease but serves as a genomic remnant or potential regulatory RNA[5]. - The presence of "pseudogene" in the name, its annotation in GeneCards, and the absence of protein-coding and functional data confirm that it is not considered a receptor, enzyme, transporter, or therapeutic target. There is nothing structurally, functionally, or pharmacologically actionable directly associated with TMEM230P2[5]. Summary: TMEM230P2 is not an actionable therapeutic target, and entries related to therapeutic action, biology, or pharmacology should be marked as null for this pseudogene[5].
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