Transmembrane protein 265 (TMEM265)

Transmembrane protein 265 (TMEM265) is a poorly characterized multi-pass transmembrane protein predicted to localize to cellular membranes. It belongs to the CECR6/TMEM121 family by sequence homology and is evolutionarily conserved, including in zebrafish and other vertebrates. There are no data in the public domain supporting a receptor, transporter, or enzyme function, nor an association with established medical disorders, drug interactions, or known biomarker status. The gene encodes a protein of uncertain physiological role, and no comprehensive functional studies or evidence of therapeutic targeting have been published to date. Key details: - Gene location: Chromosome 16 in human (Ensembl: ENSG00000281991; NCBI Gene: 100862671) - Protein length: Human isoform A0A087WTH1 (Uniprot) ~378 amino acids - Family/Domains: Predicted member of the CECR6/TMEM121 family, other domains not characterized - Expression/pattern: No verified tissue specificity or disease linkage - Experimental Data: Largely missing for molecular function, pathway involvement, or clinical relevance

Other names

IFITMD8TMEM265CECR6/TMEM121 family member (homology-based)si:ch73-271e23.6 (zebrafish ortholog)