Target intelligence / Profile preview

Transmembrane protein 267 (TMEM267)

Target
TMEM267
Molecular classification
Transmembrane protein, Protein coding gene
01

Overview

Transmembrane protein 267 is a multi-pass membrane protein encoded by the TMEM267 gene on human chromosome 5. It is conserved across vertebrates and predicted to be localized in cellular membranes. While annotated as a structural or transporter protein, its exact molecular function and involvement in biological processes are currently unknown. There is no experimental evidence supporting its therapeutic relevance, disease association, or role as a drug target. It has several transcript variants and is expressed in a range of normal and cancer tissues, but lacks functional, mechanistic, or clinical characterization. The most commonly used names and aliases include TMEM267, C5orf28, and FLJ21657. There is no evidence that TMEM267 is a therapeutic target, no reported interacting drugs, and its exact function and disease relevance remain undefined. No safety or biomarker data are available.

Other names
TMEM267Transmembrane protein 267C5orf28FLJ21657transmembrane protein C5orf28
02

Mechanism of action

Not applicable (no known drugs target this protein)

03

Biological functions

Not established (function unknown)Predicted structural molecule activityPredicted transporter activityProtein binding (inferred from physical interaction)
04

Disease associations

No defined rolesExpression profiled in cancer tissues, but no causal or mechanistic disease associations reported

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