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Transmembrane protein 270 (TMEM270)

Target: TMEM270
Molecular classification: Other (single-pass transmembrane protein; does not fit into classic receptor, transporter, enzyme, or ion channel categories)

Overview

Transmembrane protein 270 (TMEM270) is a predicted single-pass membrane protein encoded by the TMEM270 gene, located on chromosome 7q11.23 in humans. It is well conserved, but its precise function and physiological role are not characterized in the literature. TMEM270 is associated with the genomic region deleted or duplicated in Williams-Beuren syndrome but is not established as a direct causative gene. There are currently no known drugs targeting TMEM270, nor is it considered a classical therapeutic target such as a receptor, transporter, or enzyme.

Other names: WBSCR28

Biological functions

Unknown (no specific biological functions are currently well characterized)

Disease associations

Williams-Beuren syndromeWilliams-Beuren region duplication syndrome (involved by genomic location, not necessarily causal or directly implicated as a therapeutic target)

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