Transmembrane protein 38A pseudogene (TMEM38A pseudogene)

Transmembrane protein 38A pseudogene (TMEM38A pseudogene) is a noncoding genomic sequence resembling the protein-coding gene TMEM38A, a transmembrane potassium channel involved in calcium signaling[1]. Pseudogenes are genomic elements once derived from functional genes but have lost protein-coding ability due to disabling mutations or genomic rearrangements; while most pseudogenes are transcriptionally silent[5][7], some may have regulatory roles, but this is not established for the TMEM38A pseudogene[3][7]. TMEM38A itself is protein-coding and linked to monovalent cation channel activity, calcium release, and certain genetic diseases, but the pseudogene is not known to have functional, therapeutic, or disease significance[1]. Key points: - This entry is for a pseudogene, not a functional molecular target. - It does not encode a protein nor serve a therapeutic or diagnostic role. - Any disease or functional associations would arise only through rare regulatory, recombination, or mutation effects, which are not documented for this pseudogene[3][7]. If you intended a functional receptor or channel, refer to TMEM38A (Transmembrane protein 38A), not the pseudogene[1].

Other names

Transmembrane protein 38A pseudogeneTMEM38A pseudogene