Transmembrane protein 62 (TMEM62)

Transmembrane protein 62 (TMEM62) is a protein-coding gene identified in Homo sapiens, with orthologs in mouse and other vertebrates[1][10][11]. TMEM62 encodes a multi-pass transmembrane protein, but its precise physiological role remains poorly understood. Bioinformatic predictions and gene ontology annotations suggest it may have hydrolase activity and can bind calcium ions, with some potential to bind lipids, carbohydrates, or proteins[1][2][8]. TMEM62 is broadly expressed across diverse tissues, including the brain, liver, kidney, and reproductive organs[7][9]. No direct connections to drug interaction, disease causality, or established biomarker utility have been supported in current literature or large biological databases[1][5][9][10]. TMEM62 is not classified as an established therapeutic target, nor is there evidence of involvement in canonical target classes such as G protein-coupled receptors, ion channels, or enzymes involved in well-defined metabolic pathways[1][10]. No data were found to suggest that TMEM62 is misspelled, not a genuine protein-coding gene, or a non-target—however, information about its function in human health or disease is notably sparse.

Other names

FLJ23375TMEM62transmembrane protein 62