Transmembrane protein 80 (TMEM80)

Transmembrane protein 80 is a protein encoded by the TMEM80 gene in humans. It is predicted to be an integral membrane protein located in the cilium and the cell membrane, with activity associated with the ciliary transition zone. TMEM80 is implicated in biological processes such as the assembly of non-motile cilia. While mutations have been associated with some rare genetic disorders, including Meckel syndrome type 4 and pigmented basal cell carcinoma, there is currently no evidence supporting a role as a common therapeutic target, nor are there established interacting drugs or mechanistic data available[2][1][12][9].

Other names

TMEM80FLJ38216