Target intelligence / Profile preview

Transmembrane protein PMIS2 (PMIS2)

Target
PMIS2
Molecular classification
Transmembrane protein, Other
01

Overview

Transmembrane protein PMIS2 (PMIS2) is a protein-coding gene primarily characterized as a membrane-associated protein predicted to play a role in sperm function, specifically in the binding of sperm to the zona pellucida and potentially in spermatozoa motility. PMIS2 is not currently associated with any established drug interactions or recognized as a therapeutic target, and there are no well-characterized disease links or clinical applications described for this protein. Existing data chiefly define it as an intracellular or membrane-bounded organelle-associated transmembrane protein, with experimental evidence focused largely on reproductive biology, particularly fertilization processes. No adverse safety, biomarker, or direct disease implications have been established in current sources[1][3][5][7].

Other names
IFITMD9PMIS2 transmembrane protein
02

Biological functions

Sperm binding to zona pelluculaSpermatozoa mobility
03

Disease associations

Other

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