Target intelligence / Profile preview

Treponema pallidum repeat C protein (None)

Target: None
Molecular classification: Outer Membrane Protein, Tpr family, Porin

Overview

Treponema pallidum repeat C protein (TprC) is an outer membrane protein belonging to the Tpr family. It acts as a porin, facilitating transport of small molecules across the outer membrane of *Treponema pallidum*. TprC contributes to cell envelope stability and plays a role in immune evasion. It elicits strong antibody responses during syphilis infection, making it a potential target for diagnostics and vaccines. Sequence heterogeneity exists among strains, which may influence immune recognition.

Other names: TprCTPR-C

Mechanism of action

N/A

Biological functions

Porin activityCell envelope stabilityImmune evasion

Disease associations

InfectionSyphilis

Safety considerations

Potential for immune evasion

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