Target intelligence / Profile preview

Triglyceride (None)

Target: None
Molecular classification: Lipid, Ester

Overview

Triglycerides are a type of fat (lipid) that serve as the main form of stored energy in humans and most animals. They are esters derived from glycerol and three fatty acids. High levels are associated with increased cardiovascular risk.

Other names: TGTAGTriacylglycerol

Mechanism of action

Drugs lower triglyceride levels through various mechanisms, including inhibiting VLDL production, increasing lipoprotein lipase activity, and reducing hepatic triglyceride synthesis.

Biological functions

Energy storageEnergy source

Disease associations

Cardiovascular diseaseMetabolic syndromeObesityDiabetes

Safety considerations

HypertriglyceridemiaIncreased risk of cardiovascular eventsPancreatitis (in severe cases)

Interacting drugs

Fibrates

3 more in the full profile.

Biomarkers

Triglyceride levels

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