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Target intelligence / Profile preview
Trichomonas vaginalis (T. vaginalis)
- Target
- T. vaginalis
- Molecular classification
- Protozoan parasite
01
Overview
*Trichomonas vaginalis* is an anaerobic flagellated protozoan parasite that causes trichomoniasis, a common sexually transmitted infection affecting the urogenital tract. It is associated with adverse health outcomes, including increased risk of HIV acquisition and preterm birth. The parasite is treatable with metronidazole or tinidazole, but resistance to these drugs is a growing concern.
- Other names
- Trichomonas*Trichomonas vaginalis*
02
Mechanism of action
Metronidazole and Tinidazole: Inhibit hydrogenosome metabolism, leading to cell death. Carmaphycin-17: Inhibits proteasome, disrupting protein degradation pathways.
03
Biological functions
Infectionpathogenesis
04
Disease associations
Sexually transmitted infectionfemale reproductive tract infectionmale urethral infection
05
Safety considerations
Resistance to metronidazolepotential for spreading other STIs like HIV
06
Interacting drugs
Metronidazole
2 more in the full profile.
07
Biomarkers
Vaginal discharge in womenurethral discharge in men
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