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Triggering receptor expressed on myeloid cells 1 pseudogene

Molecular classification: Other (Pseudogene)

Overview

Triggering receptor expressed on myeloid cells 1 pseudogene is a DNA sequence that is homologous to the functional TREM-1 gene but does not encode a functional protein. Pseudogenes typically arise from gene duplication or retrotransposition events and accumulate mutations that render them non-functional. While the functional TREM-1 receptor plays a key role in amplifying immune responses and inflammatory signaling[3][1][4][5], the pseudogene variant (ENSG00000278745) lacks biological function and disease relevance, and is not implicated in any mechanisms of action, disease roles, or therapeutic targeting.

Other names: TREM1PTriggering receptor expressed on myeloid cells 1 pseudogene

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