Target intelligence / Profile preview

Triglyceride Synthesis (TAG Synthesis)

Target: TAG Synthesis
Molecular classification: Metabolic Process, Lipid Metabolism

Overview

Triglyceride synthesis, also known as triacylglycerol (TAG) synthesis, is the biochemical process by which three fatty acid molecules are esterified to a glycerol backbone. This process primarily occurs in adipose tissue and the liver, but also takes place in other tissues such as the intestine. The resulting triglycerides serve as major energy storage molecules in animals. Abnormalities or dysregulation of triglyceride synthesis can lead to metabolic disorders.

Other names: Triacylglycerol SynthesisFat Synthesis

Biological functions

Energy StorageLipid MetabolismVLDL Assembly/Transport

Disease associations

ObesityNon-alcoholic Fatty Liver DiseaseHypertriglyceridemiaInsulin ResistanceType 2 Diabetes MellitusCardiovascular DiseasesMetabolic Syndrome

Safety considerations

Dysregulation can lead to metabolic disorders

Biomarkers

Triglyceride levels

Beyond the preview

Go deeper on Triglyceride Synthesis (TAG Synthesis).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Triglyceride Synthesis (TAG Synthesis).

Explore the full profile