Target intelligence / Profile preview

Triiodothyronine (T3)

Target: T3
Molecular classification: Endogenous hormone, Thyroid hormone, Small molecule

Overview

Triiodothyronine (T3) is a thyroid hormone that plays a central role in regulating metabolism, growth, development, and numerous physiological processes throughout the body. It is the most biologically active thyroid hormone and primarily acts by binding to nuclear Thyroid Hormone Receptors (TRs) to regulate gene expression.

Other names: T3

Mechanism of action

Nuclear receptor-mediated gene regulation

Biological functions

Regulates metabolismRegulates growthRegulates developmentRegulates temperatureRegulates cardiac outputGene regulation

Disease associations

HyperthyroidismHypothyroidism

Safety considerations

Abnormal thyroid hormone levels

Biomarkers

Serum total triiodothyronineFree triiodothyronine

Beyond the preview

Go deeper on Triiodothyronine (T3).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Triiodothyronine (T3).

Explore the full profile