TRIM67 antisense RNA 1 (TRIM67-AS1)

TRIM67 antisense RNA 1 (TRIM67-AS1) is a long non-coding RNA (lncRNA) transcribed from the antisense strand of the TRIM67 gene region[5]. As an antisense RNA, it regulates the expression of its sense counterpart gene (TRIM67) at various levels—potentially affecting transcription, splicing, mRNA stability, or translation[3]. Antisense RNAs like TRIM67-AS1 may act either in cis (local effects on the same chromosome) or in trans (distant loci); their main function generally involves modulation of gene expression through RNA-RNA or chromatin-associated mechanisms[3]. While the protein-coding gene TRIM67 is implicated in cancer biology and neuronal differentiation, evidence specifically implicating TRIM67-AS1 itself as a direct therapeutic target or drug-interacting entity is lacking; its main role is as a regulatory non-coding RNA[3][5]. No approved therapies are known to specifically target TRIM67-AS1, and its primary relevance at present appears to be in molecular research and potentially as a disease biomarker in cancer.

Other names

TRIM67-AS1TRIM67 Antisense RNA 1