Triosephosphate isomerase 1 pseudogene 2 (TPI1P2)

Triosephosphate isomerase 1 pseudogene 2 (TPI1P2) is a processed, intronless pseudogene in the human genome with high sequence similarity to the functional TPI1 gene but contains mutations that prevent the synthesis of an active triosephosphate isomerase enzyme[1][2][4]. Pseudogenes such as TPI1P2 do not code for functional proteins, and no direct biological role or disease involvement is established for this locus. The functional triosephosphate isomerase enzyme is a key metabolic enzyme involved in glycolysis, but only the actual TPI1 gene encodes active protein; TPI1P2 does not[1][2][4].\n\nIf you seek structured information for a drug target, it should be based on the parent functional gene, TPI1, not TPI1P2, as TPI1P2 is a non-functional pseudogene.

Other names

Putative triosephosphate isomerase-like protein LOC286016TPI1P2