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Tripartite motif containing 49B (TRIM49B) is a protein coding gene encoding a member of the TRIM (tripartite motif-containing) protein family. TRIM proteins typically possess a RING-type zinc finger domain, B-box domain, and coiled-coil region, and function predominantly as E3 ubiquitin ligases involved in protein ubiquitination and degradation. TRIM49B is predicted to be active in the cytoplasm and involved in innate immune responses and gene expression regulation. Its precise physiological role, disease associations, or interactions with drugs have not been established, and it is not currently considered a characterized therapeutic target[1][2][4][5][7].
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