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Target intelligence / Profile preview
Tripartite Motif-Containing Protein 42 (TRIM42)
- Target
- TRIM42
- Molecular classification
- Tripartite Motif-Containing Protein, Ubiquitin Protein Ligase
01
Overview
The TRIM42 protein is a member of the tripartite motif-containing family, which includes three zinc-binding domains (RING, B-box type 1, and B-box type 2) and a coiled-coil region. It is predicted to enable ubiquitin protein ligase activity and is involved in protein ubiquitination. TRIM42 is associated with diseases such as astigmatism and wrinkly skin syndrome, and it has a paralog in TRIM27. Despite its role in ubiquitination, its specific therapeutic applications or interactions with drugs are not well-documented in the available literature.
- Other names
- Tripartite Motif Containing 42FLJ40097PPP1R40T4A1Protein Phosphatase 1, Regulatory Subunit 40
02
Biological functions
Protein UbiquitinationInnate ImmunityZinc Ion Binding
03
Disease associations
AstigmatismWrinkly Skin Syndrome
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