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Tripartite motif-containing protein 64B (TRIM64B)

Target: TRIM64B
Molecular classification: Other (Tripartite motif-containing family, RING-type E3 ubiquitin ligase superfamily)

Overview

Tripartite motif-containing protein 64B (TRIM64B) is a putative member of the TRIM protein family, characterized by a conserved RBCC motif containing a RING domain, one or two B-box domains, and a coiled-coil domain[1][2][4]. TRIM64B is predicted to have ubiquitin protein ligase (E3 ligase) activity, and to be involved in the innate immune response and regulation of gene expression, functioning primarily in the cytoplasm[1][5][6]. However, there are currently no reports associating TRIM64B directly with specific human diseases, therapeutic interventions, or interacting drugs. TRIM64B remains poorly characterized, with much of its molecular and biological function inferred from its membership in the broader TRIM family—which is involved in processes such as autophagy, immunity, and protein regulation[2][4]. There is no strong evidence currently supporting TRIM64B as a direct therapeutic target.

Other names: Tripartite motif-containing protein 64BTRIM64BPutative tripartite motif-containing protein 64B

Biological functions

Ubiquitin protein ligase activity (predicted)Innate immune response (predicted)Regulation of gene expression (predicted)

Disease associations

Other (no specific disease associations or roles identified in the literature)

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